One of the sites I like to check out is Open Jason, today he lists 130 sites that can help you get organized. Lots of computer Web 2 goodies.
My personal organization tool is Remember the Milk which I have on my iGoogle page, along with a day timer that I keep on the computer desk where I scribble all sorts of things I need to remember. I do try and keep from little pieces of paper all over the place. I also keep a copy of needed info in Google Docs so I can access that from any computer. My passwords for example, and before you exclaim with shock that I would do this, I leave myself a message like "welshword hubby's forces demob date" and that is enough of a prompt for me to remember what the password was. I haven't found anything I like better than this, although I am sure there must be something. While mentioning Google Docs I have a Firefox extension that I love called GDocs Sidebar which allows me quick access to documents that I store online. I don't bother to store much on my computer as I may need it on the other one. So both computer hard drives are relatively clean although I do have a few notes on my laptop that I might need if I can't access the Internet on our trip to Mexico and I used Picasa 3 to store photos and upload to the Internet. I clean up anything I don't want as I go rather than tie up a lot of space. I am a bit compulsive about keeping my hard drive clean.
Also since I am now running my desktop computer and my laptop I am careful to use Google Bookmarks which I can access from both computers, or any other computer, rather than just bookmark a page in Favourites. I like Google Notebook which helps with bookmarks also as you can tag them and type a note to attach to the Bookmark and that too can be accessed from any computer.
How about you, do you have a method that works well for you?